C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 311/08 (2006.01) A61K 31/37 (2006.01) A61K 31/38 (2006.01) C07D 311/16 (2006.01) C07D 407/04 (2006.01) C07D 409/04 (2006.01)
Patent
CA 2138021
The present invention provides compounds having 12- lipoxygenase inhibitory effect and medicines inhibiting 12-lipoxygenase selectively, and relates to novel coumarin derivatives and medicines containing the compounds as effective ingredients. Furthermore, this invention relates to compounds capable of converting to compounds inhibiting 12-lipoxygenase activities selectively according to the cleavage of modified moieties in vivo and medicines inhibiting 12- lipoxygenase selectively, and relates to novel coumarin derivatives having acyl groups as modified moieties and medicines containing the compounds as effective ingredients. The compounds of the present invention can inhibit 12-lipoxygenase strongly and selectively, and being useful as medicines for preventing and treating various circulatory diseases such as arteriosclerosis and vasospasm and for preventing of the metastasis of some kinds of cancers, and show low toxicity and few side effects.
Hamano Hirokazu
Hashimoto Koichi
Mori Shigehiro
Moriuchi Hisako
Yamada Akio
Ltd. Morinaga Milk Industry Co.
Swabey Ogilvy Renault
LandOfFree
Coumarin derivative and use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Coumarin derivative and use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Coumarin derivative and use thereof will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1428471