C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/207, 260/279
C07D 311/16 (2006.01) C07D 405/06 (2006.01) C07D 413/06 (2006.01)
Patent
CA 1258455
ABSTRACT OF THE DISCLOSURE A compound is provided herein having the formula: Image (I) wherein R1 is halogen, an unsubstituted hydrocarbyl group, or a hydrocarbyl group substituted with hydroxyl, amino or carbonyl groups and which can be interrupted in the carbon atom chain by O, S or N: wherein R2, R6 and R7, which may be the same or different, each represents hydrogen. an unsubstituted hydrocarbyl group, or a hydrocarbyl group substituted with hydroxyl, amino or carbonyl groups and can be interrupted in the carbon atom chain by O, S or N, or R6 and R7 taken together may represent a hetero group having one or more hetero atoms; wherein R3 and R4, which may be the same or different, each represents an unsubstituted hydrocarbyl group, or a hydrocarbyl group substituted with hydroxyl, amino or carbonyl groups and can be interrupted in the carbon atom chain by O, S or N, or wherein R3 and R4 taken together may represent an alkylene group or a hetero group having one or more hetero atoms: and wherein R5 is hydrogen, an unubstituted hydrocarbyl group or a hydrocarbyl group Abstract of the Disclosure - Page 2 substituted with hydroxyl, amino or carbonyl groups and can be interrupted in the carbon atom chain by O, S or N, halogen or a free or protected hydroxy group, or a pharmaceutically acceptable salt thereof. The compounds have antiaggregating properties and some of them also have antitumor and antimetastatic activity.
459548
Della Valle Francesco
Romeo Aurelio
Borden Ladner Gervais Llp
Fidia S.p.a.
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