Coumarin derivatives with comt inhibiting activity

Details Coumarin derivatives with comt inhibiting activity Coumarin derivatives with comt inhibiting activity

C - Chemistry, Metallurgy

07

D

C07D 311/04 (2006.01) A61K 31/435 (2006.01) A61K 31/47 (2006.01) A61P 25/16 (2006.01) C07D 215/20 (2006.01) C07D 311/16 (2006.01) C07D 311/76 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2414787

Compounds of formula (I') wherein the two OH- substituents in the phenyl moiety are in a position ortho to one another and R1 in a position ortho to one of the hydroxy groups; and X, R1 to R6 are as defined in claims, exhibit COMT enzyme inhibiting activity so that they are useful as COMT inhibitors.

La présente invention concerne des composés de formule (I') dans laquelle: les substituants OH- de la fraction phényle se trouvent dans une position ortho l'un par rapport à l'autre, et R1 se trouve dans une position ortho par rapport à l'un des groupes hydroxy; et X, R¿1? à R¿6? correspondent aux éléments indiqués dans les revendications. Lesdits composés présentent une activité d'inhibition de l'enzyme COMT de sorte qu'ils peuvent être utilisés comme inhibiteurs de la COMT.

Affiliated with

Also associated with

Rating

Coumarin derivatives with comt inhibiting activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Coumarin derivatives with comt inhibiting activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Coumarin derivatives with comt inhibiting activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1814789