Coupling of an anti-tumor to an antibody using...

Details Coupling of an anti-tumor to an antibody using... Coupling of an anti-tumor to an antibody using...

A - Human Necessities

61

K

167/103, 167/139

A61K 47/48 (2006.01)

Patent

CA 2021942

The present invention relates to antitumor compounds of the formula I: (see formula I) wherein M is selected from the group consisting of an hydrogen atom, a peptide residue, and a protein residue linked to the carbon atom via the amino residue of .epsilon.-lysine present therein which can be an antibody used to target the anti-tumor agent to the malignant cells, and R can be an antitumor agent such as daunorubicin, doxorubicin, or an epirubicin derivative.

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