Coupling reagent of immuno-active molecule to an enzyme

Details Coupling reagent of immuno-active molecule to an enzyme Coupling reagent of immuno-active molecule to an enzyme

C - Chemistry, Metallurgy

12

N

167/45, 195/35.3

C12N 9/96 (2006.01) A61K 47/48 (2006.01) C07D 207/404 (2006.01) C12N 11/06 (2006.01) G01N 33/535 (2006.01)

Patent

CA 1120398

ABSTRACT OF THE DISCLOSURE Novel enzyme conjugates useful in immunoassay methods are prepared with the use of a novel coupling reagent of N- succinimidyl (4-iodoacetyl) aminobenzoate by reacting the coupling reagent, firstly, with an amino-containing macro- molecule, and, thereafter, with a sulfhydryl-containing enzyme, the enzyme conjugate prepared in a high yield and of high specificity.

324089

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