A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
167/323
A61L 27/00 (2006.01) A61L 33/00 (2006.01)
Patent
CA 1302896
COVALENT ATTACHMENT OF ANTICOAGULANTS AND THE LIKE ONTO BIOMATERIALS Abstract of the Disclosure A substrate for medical devices and a process for making the substrate is provided, the substrate having on at least part of its surface a blood-compatible surface produced by coupling a physiologically active substance to the surface. The physiologically active substance is one having an inhibitory effect on the formation of blood clots and/or is capable of breaking down blood clots formed. The physiologically active substance is bonded to a polyacid, and the polyacid is attached to the surface by a covalent bond.
568868
Engbers Gerardus Henricus Maria
Feijen Jan
Cordis Europa N.v.
Osler Hoskin & Harcourt Llp
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