Covalent attachment of nucleic acid molecules onto...

Details Covalent attachment of nucleic acid molecules onto... Covalent attachment of nucleic acid molecules onto...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2252911

Methods for the covalent, specific and reversible immobilization of nucleic acid molecules onto solid-phases by means of a reversible disulfide bond for nucleic acid molecule array preparation are described. These methods can be used to prepare reusable nucleic acid molecule arrays with high specificity and high efficiency.

L'invention porte sur des procédés d'immobilisation covalente, spécifique et réversible de molécules d'acide nucléique sur des phases solides au moyen de ponts disulfures pour la préparation de réseaux de molécules d'acide nucléique. Ces procédés peuvent servir à préparer des réseaux de molécules d'acide nucléique réutilisables avec une grande spécificité et une grande efficacité.

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