Covalently cross-linked oligonucleotides

Details Covalently cross-linked oligonucleotides Covalently cross-linked oligonucleotides

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01)

Patent

CA 2131311

Covalent cross-linkages for two oligonucleotide strands or for first and second regions of a single oligonucleotide strand connect sugar moieties of nucleotides on the respective strands or the regions of the single strand. The cross-linkages are connected to at least one strand or region via a space-spanning group. The cross-linkage also can be connected to the other strand or other region via a space-spanning group or via an abasic site located on the other strand or other region.

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