Cpg oligonucleotide analogs containing hydrophobic t analogs...

Details Cpg oligonucleotide analogs containing hydrophobic t analogs... Cpg oligonucleotide analogs containing hydrophobic t analogs...

C - Chemistry, Metallurgy

12

N

C12N 15/117 (2010.01) A61K 31/7125 (2006.01) A61P 37/04 (2006.01) C07H 21/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2664219

The invention relates to oligonucleotides including at least one lipophilic substituted nucleotide analog and a pyrimidine- purine dinucleotide. The invention also relates to pharmaceutical compositions and methods of use thereof.

L'invention concerne des oligonucléotides comprenant au moins un analogue nucléotidique substitué lipophile et un dinucléotide de pyrimidine-purine. L'invention concerne également des compositions pharmaceutiques et des procédés d'utilisation de celles-ci.

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