C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/67 (2006.01) C12N 15/81 (2006.01) C12N 15/82 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2456718
A method of creating a nucleic acid sequence having an adenine-rich nucleic acid block of at least 25 nucleotides in length is provided, whereby said nucleic acid sequence is capable of causing translation by internal ribosome entry (IRES element). Said adenine-rich nucleic acid block comprises from 40 to 100 mol-% adenine.
L'invention concerne un procédé permettant de créer une séquence d'acide nucléique comprenant un bloc d'acide nucléique riche en adénine d'une longueur d'au moins 25 nucléotides. Cette séquence d'acide nucléique est capable de provoquer une traduction par entrée interne des ribosomes (élément IRES). Ce bloc d'acide nucléique riche en adénine comprend de 40 à 100 % mol. d'adénine.
Atabekov Joseph
Dorokhov Yurii
Gleba Yuri
Ivanov Peter
Skulachev Maxim
Icon Genetics Inc.
Smart & Biggar
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