A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 1/02 (2006.01) A61L 27/38 (2006.01) C12M 3/00 (2006.01) C12N 5/00 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2330104
A method of providing a vascularized, three-dimensional tissue in a living subject is disclosed. The method includes the steps of (a) creating, from a biocompatible material capable of supporting cell adhesion, growth, and migration, a porous construct containing cells to be transplanted, and (b) delivering the construct into an area of interest in the living subject to form a vascularized three-dimensional tissue. The preferred construct has a dimension in which it is about 50 µm to about 500 µm from the outermost surface to the center of the construct. The preferred construct also has an interconnected porous structure having a pore size of from about 10 µm to no greater than 300 µm. The cells within the preferred construct are no greater than 250 µm from an outer surface of the construct.
L'invention concerne un procédé d'apport d'un tissu tridimensionnel vascularisé dans un sujet vivant. Le procédé consiste à) à créer à partir d'une matière biocompatible capable de support l'adhésion, la croissance et la migration cellulaires, une construction poreuse contenant des cellules à transplanter et b) à administrer la construction dans une zone d'intérêt dans le sujet vivant pour former un tissu tridimensionnel vascularisé. La construction préférentielle présente une dimension dont la distance de la surface la plus externe au centre de la construction mesure entre environ 50 µm et environ 500 µm. La construction préférentielle présente aussi une structure poreuse interconnectée dont la granulométrie des pores est de l'ordre d'environ 10 µm ne dépassant pas 300µm. Les cellules contenues dans la construction préférentielle ne dépassent pas une distance de 250 µm à partir de la surface externe de la construction.
Halberstadt Craig R.
Holder Walter D. Jr.
Charlotte-Mecklenberg Hospital Authority
Halberstadt Craig R.
Holder Walter D. Jr.
Mbm & Co.
LandOfFree
Creation of three-dimensional tissues does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Creation of three-dimensional tissues, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Creation of three-dimensional tissues will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1778543