Crf receptor antagonists and methods relating thereto

Details Crf receptor antagonists and methods relating thereto Crf receptor antagonists and methods relating thereto

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2550948

CRF receptor antagonists are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, such as stroke. The CRF receptor antagonists of this invention have the following structure (I), including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, Y, Ar, and Het are as defined herein. Compositions containing a CRF receptor antagonist in combination with a pharmaceutically acceptable carrier are also disclosed, as well as methods for use of the same.

Antagonistes du recepteur de CRF trouvant application dans le traitement de différents troubles et notamment dans le traitement des troubles impliquant une hypersécrétion de CRF chez les animaux homéothermes, par exemple les accidents vasculaires cérébraux. Lesdits antagonistes du recepteur de CRF présentent la structure (I). Il peut également s'agir de leurs stéréoisomères, promédicaments et sels pharmaceutiquement acceptables. Dans ladite structure, R¿1?, R¿2?, R¿3?, Y, Ar et Het ont les définitions données dans la présente demande. On a également prévu des compositions renfermant un antagoniste du recepteur de CRF en association avec un excipient pharmaceutiquement acceptable, ainsi que leur procédé de mise en oeuvre.

Affiliated with

Also associated with

Rating

Crf receptor antagonists and methods relating thereto does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Crf receptor antagonists and methods relating thereto, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crf receptor antagonists and methods relating thereto will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1514734