Crfg-1, a target and marker for chronic renal failure

Details Crfg-1, a target and marker for chronic renal failure Crfg-1, a target and marker for chronic renal failure

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2228742

Chronic renal failure gene-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing chronic renal failure gene-1 polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal disease, renal ischemia, diabetic nephropathy, acute renal failure, and Alzheimer's disease, among others, and diagnostic assays for such conditions.

Polypeptides et polynucléotides du gène-1 de l'insuffisance rénale chronique et méthodes pour obtenir ces polypeptides par les techniques de l'ADN recombinant. Sont également décrites des méthodes permettant d'utiliser les polypeptides et polynucléotides du gène-1 de l'insuffisance rénale chronique dans la conception de protocoles pour traiter, entre autres affections, les néphropathies chroniques, l'ischémie rénale, la néphropathie diabétique, l'insuffisance rénale aiguë et la maladie d'Alzheimer, de même que les épreuves diagnostiques pour ces affections.

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