C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2236248
CRFG-la polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CRFG-la polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal disease, renal ischemia diabetic nephropathy, acute renal failure, Neurodegenerative disease, and Alzheimer's disease, among others, and diagnostic assays for such conditions.
Polypeptides et polynucléotides du CRFG-1a et méthode pour obtenir ces polypeptides par la technique de l'ADN recombinant. Sont également décrites une méthode permettant d'utiliser les polypeptides et polynucléotides du CRFG-1a dans la conception de protocoles pour le traitement des néphropathies chroniques, de l'ischémie rénale, de la néphropathie diabétique, de l'insuffisance rénale aiguë, des maladies neurodégénérataives et de la maladie d'Alzheimer, entre autres affections, de même que les épreuves diagnostiques pour détecter ces affections.
Laping Nicholas J.
Olson Barbara
Zhu Yuan
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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