Crfr1 selective ligands

Details Crfr1 selective ligands Crfr1 selective ligands

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C07K 14/575 (2006.01) C07K 14/695 (2006.01)

Patent

CA 2455223

CRF peptide analogs that bind to CRFR1 with an affinity far greater than they bind to CRFR2. These analogs exhibit CRF agonist activity.

L'invention concerne des analogues peptidiques CRF qui se lient au CRFR1 avec une plus forte affinité qu'au CRFR2. Ces analogues présentent une activité agoniste CRF.

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