C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2593212
Humanized forms of an anti-CRIPTO antibody and portions thereof. In one embodiment, the variable regions of these antibodies or polypeptides comprising them (e.g., full-length antibodies or domain deleted antibodies) can be used to treat disorders, such as cancer.
L'invention concerne des formes humanisées d'un anticorps anti-CRIPTO et des portions de celui-ci. Dans une forme d'exécution, les régions variables de ces anticorps ou polypeptides les renfermant (par exemple, des anticorps pleine longueur ou des anticorps à domaine effacé) peuvent être utilisées pour traiter des maladies telles que le cancer.
Garber Ellen
Glaser Scott
Lugovskoy Alexey Alexandrovich
Saldanha Jose William
Sanicola-Nadel Michele
Biogen Idec Ma Inc.
Gowling Lafleur Henderson Llp
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