Cripto mutant and uses thereof

Details Cripto mutant and uses thereof Cripto mutant and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2422814

The present invention is based on the discovery that CRIPTO mutants each comprising at least one amino acid substitution from a CRIPTO polypeptide demonstrate tumor blocking activity.

La présente invention se rapporte à la découverte que les mutants CRIPTO qui comprennent chacun au moins une substitution d'acide aminé par rapport à un polypeptide CRIPTO présentent une activité de blocage des tumeurs. .

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