Crisp polypeptides as contraceptives and inhibitors of sperm...

Details Crisp polypeptides as contraceptives and inhibitors of sperm... Crisp polypeptides as contraceptives and inhibitors of sperm...

A - Human Necessities

61

K

A61K 38/17 (2006.01) A61P 15/16 (2006.01) A61P 15/18 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2487419

Included in the present invention are methods of inhibiting sperm capacitation, inhibiting the phosphorylation of a protein at tyrosine residues, inhibiting an acrosomal reaction, and inhibiting fertilization of an egg by sperm with the administration of a CRISP polypeptide.

la présente invention concerne notamment des procédés d'incapacitation du sperme, d'inhibition de la phosphorilation d'une protéine au niveau de résidus de tyrosine, d'inhibition de réaction acrosomique et d'inhibition de la fertilisation d'un oeuf par du sperme, ceci par administration d'un polypeptide CRISP.

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