C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01)
Patent
CA 2728763
Provided are methods and compositions for selectively targeting CRKL through the use of target-ing peptides. Selective targeting of secreted CRKL through the use of a targeting peptide may be used, for example, in the treatment of cancer to deliver a chemotherapeutic compound, fusion protein, or fusion construct to a cancer cell or tissue.
La présente invention concerne des procédés et des compositions de ciblage sélectif de CRKL à l'aide de peptides de ciblage. Il est possible de mettre en oeuvre un ciblage sélectif de CRKL sécrété à l'aide d'un peptide de ciblage par exemple dans le cadre d'un traitement anticancéreux, pour administrer un composé chimiothérapeutique, une protéine de fusion ou une construction de fusion à une cellule cancéreuse ou à un tissu cancéreux.
Arap Wadih
Mintz Paul J.
Pasqualini Renata
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Board Of Regents Of The University Of Texas System
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