A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/38 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/20 (2006.01)
Patent
CA 2336570
The present invention describes the use of croscarmellose sodium to coat bitter-tasting active agents in a manner that will mask the bitter taste of these materials, taste masked pharmaceutical compositions in which the particles of pharmaceutically active agent are coated with croscarmellose sodium, taste masked pharmaceutical tablets made therefrom, in which the rapid disintegration of tablets that is imparted by croscarmellose sodium is preserved, and to a method for preparing such coated particles by preparing them in a fluidized bed coating process.
La présente invention concerne l'utilisation de croscarmellose de sodium pour enrober des principes actifs de goût amère, de façon à masquer l'amertume de ces matières, des compositions pharmaceutiques de saveur masquée dans lesquelles les particules de principe actif pharmaceutique sont recouvertes de croscarmellose de sodium, des tablettes pharmaceutiques de ces compositions, pour lesquelles la désintégration rapide apportée par le croscarmellose de sodium est conservée, et un procédé de préparation de telles particules enrobées au moyen d'un procédé d'enrobage en lit fluidisé.
Augello Michael
Dell Sheila M.
Dimemmo Lynn M.
Reier George E.
Stamato Howard J.
Fmc Corporation
R.p. Scherer Technologies Inc.
Smart & Biggar
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