Cross-linked collagen and uses thereof

Details Cross-linked collagen and uses thereof Cross-linked collagen and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/78 (2006.01) A61K 38/39 (2006.01)

Patent

CA 2687990

The present invention discloses collagen cross-linked in a micro to non-fibrillar form and at a high concentration. The cross-linked collagen gel has improved volume stability or persistence than collagen cross- linked at a neutral pH. Also disclosed are methods for preparing the inventive cross-linked collagen and using such for augmenting soft tissues in mammals.

L'invention porte sur du collagène réticulé sous une forme microfibrillaire à non fibrillaire et en concentration élevée. Le gel collagène réticulé de l'invention possède une stabilité ou persistance volumétrique améliorée par rapport au collagène réticulé à un pH neutre. L'invention concerne également des procédés de préparation du collagène réticulé précité et des procédés d'utilisation de ce dernier pour augmenter les tissus mous chez les mammifères.

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