Cross-linked copolymer

Details Cross-linked copolymer Cross-linked copolymer

C - Chemistry, Metallurgy

08

F

88/40, 402/405,

C08F 220/26 (2006.01) A61L 27/16 (2006.01) C08F 226/06 (2006.01) G02B 1/04 (2006.01) G02C 7/04 (2006.01)

Patent

CA 1037196

ABSTRACT A copolymeric hydrogel for contact lenses with physiological saline uptake 65-85% is formed from an N-vinyl lactam e.g. N-vinyl-2-pyrrolidone and up to 15% of a hydrophobic comonomer of formula Ch2 - Image - CO - X - R2 where R1 is H or C1-C4 alkyl (preferably methyl) X is -O- or -NH- and R2 is aryl, C1-C6 alkyl substituted by aryl or aryloxy, or C1-C6 alkoxy substituted by aryl or aryloxy. Preferably the aryl or aryloxy group contain one or two six-membered carbocyclic aromatic rings; they may be C1-C4 alkyl, C1-C4 alkoxy, or halogen, substituted. Crosslinking agents used preferably have their two functional groups differing in reactivity e.g. allyl, or 3-allyloxy-2-hydoxy- propyl, methacrylates.

230799

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