Cross-linked glycopeptide-cephalosporin antibiotics

Details Cross-linked glycopeptide-cephalosporin antibiotics Cross-linked glycopeptide-cephalosporin antibiotics

C - Chemistry, Metallurgy

07

D

C07D 501/00 (2006.01) A61K 31/545 (2006.01) A61K 38/04 (2006.01) A61P 31/00 (2006.01) C07D 277/40 (2006.01) C07D 277/42 (2006.01) C07D 501/20 (2006.01) C07K 9/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2463544

This invention provides cross-linked glycopeptide cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.

L'invention concerne des composés réticulés de glycopeptide-céphalosporine et des sels pharmaceutiquement acceptables de ceux-ci, qui sont utiles comme antibiotiques. L'invention concerne aussi des compositions pharmaceutiques contenant ces composés ; des méthodes de traitement d'infections bactériennes chez un mammifère à l'aide de ces composés ; et des procédés et des produits intermédiaires utiles pour préparer ces composés.

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