C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/071 (2010.01) A61F 2/00 (2006.01) A61L 27/26 (2006.01) A61L 27/28 (2006.01) A61L 27/44 (2006.01) A61L 31/06 (2006.01) A61L 31/10 (2006.01) C08J 3/075 (2006.01) C08L 5/08 (2006.01) C08L 89/00 (2006.01) C12N 11/10 (2006.01)
Patent
CA 2428748
The present invention concerns universal biocompatible matrices comprising cross-linked hyaluronic acid-laminin gels useful for clinical applications including as implants, for tissue engineering as well as in biotechnology. The gel matrices according to the present invention may be used clinically either per se or as a cell bearing implant- The gels are particularly useful for use for transplantation to the nervous system or as a coating or a scaffold for use on medical devices including stents.
La présente invention concerne des substances fondamentales biocompatibles et universelles comprenant des gels de laminine et d'acide hyaluronique réticulé utiles pour des applications cliniques, y compris en tant qu'implants, en génie tissulaire et également en biotechnologie. Les matrices de gel selon l'invention peuvent être utilisées cliniquement soit telles quelles, soit comme un implant porteur de cellules. Les gels sont particulièrement utiles à des fins de transplantation dans le système nerveux ou pour former un enrobage ou une structure destinés à être utilisés sur des dispositifs médicaux, y compris les stents.
Nevo Zvi
Rochkind Shimon
Shahar Abraham
N.v.r. Labs Bvi
Ridout & Maybee Llp
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