Cross-linked hydrogel containing an active substance

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/36 (2006.01) A61K 47/48 (2006.01) C08J 3/075 (2006.01) C08J 3/24 (2006.01) C08L 5/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2706183

The invention relates to a biocompatible metastable intermediate material for controlling the mobility of at least one biologically active substance. An example of the invention is a hydrogel formed by cross-linked sodium hyaluronate treated with an oxidizing agent so as to open sugar rings and form aldehyde groups. The gel according to the invention is sterilized, e.g. by autoclaving.

L'invention porte sur un matériau intermédiaire métastable biocompatible pour contrôler la mobilité d'au moins une substance biologiquement active. Un exemple de l'invention est un hydrogel formé par de l'hyaluronate de sodium réticulé traité par un agent oxydant de façon à ouvrir les cycles de sucre et à former des groupes aldéhydes. Le gel selon l'invention est stérilisé, par exemple par autoclave.

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