C - Chemistry – Metallurgy – 09 – H
Patent
C - Chemistry, Metallurgy
09
H
C09H 5/00 (2006.01) A23J 3/06 (2006.01) A23L 1/0562 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 38/22 (2006.01) A61K 38/58 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61L 27/34 (2006.01) C07K 14/78 (2006.01) C09H 1/00 (2006.01) C12P 21/02 (2006.01) G03C 1/047 (2006.01) G03C 1/30 (2006.01)
Patent
CA 2273498
Enzymatically cross-linked protein gels and methods for preparing them are disclosed. The methods comprise adding a transglutaminase, such as factor XIII, to a composition of a temperature- sensitive gel-forming protein, such as gelatin or collagen, and incubating the composition and transglutaminase under gel-forming conditions. The resulting gels have superior strength and thermal stability, and can be used within a variety of medical and industrial applications.
Gels de protéines réticulées par action enzymatique et leurs procédés de fabrication. Les procédés consistent à ajouter une transglutaminase telle que le facteur XIII à une composition formée par une protéine thermosensible et gélifiante telle que la gélatine ou le collagène, et à incuber la composition et la transglutaminase dans des conditions favorisant la formation de gels. Les gels qui en résultent possèdent une résistance et une stabilité thermique accrues et peuvent avoir de nombreuses applications médicales ou industrielles.
Bishop Paul D.
Lasser Gerald
Ledgley Law
Zymogenetics Inc.
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