Cross-linking process of carboxylated polysaccharides

Details Cross-linking process of carboxylated polysaccharides Cross-linking process of carboxylated polysaccharides

C - Chemistry, Metallurgy

08

B

C08B 15/00 (2006.01) C08B 31/00 (2006.01) C08B 37/04 (2006.01) C08B 37/08 (2006.01)

Patent

CA 2350665

A process for the preparation of cross-linked polysaccharides containing carboxy groups, allowing complete control of cross-linking degree as well as high reproducibility in terms of constant characteristics of the final product. The process comprises a first step: activation of the carboxy groups in anhydrous aprotic solvent and then the reaction with a polyamine. The obtained cross-linked polysaccharide may be subjected to sulphation of the five hydroxy groups.

L'invention concerne une technique de préparation des polysaccharides réticulés contenant des groupes carboxy, qui permet un contrôle complet du degré de réticulation, et une reproductibilité élevée en termes de caractéristiques constantes du produit final. Cette technique consiste à activer les groupes carboxy du polysaccharide dans un solvant aprotique anhydre, et à faire réagir le polysaccharide obtenu avec une polyamine. Le polysaccharide réticulé obtenu peut être soumis à une sulfatation des cinq groupes hydroxy.

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