Cross-species chromosome painting

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01)

Patent

CA 2282788

The invention provides methods and reagents for detecting a chromosomal aberration in an animal chromosome or karyotype. One or more detectably- labeled chromosome-specific probes from a first animal species are hybridized to chromosomes of a second animal species. This results in a banding pattern that can be compared to the pattern found in a normal chromosome or karyotype.

L'invention porte sur des procédés et des réactifs qui permettent de détecter une aberration chromosomique dans un chromosome animal ou caryotype. Une ou plusieurs sondes à spécificité chromosomique marquées de manière décelable d'une première espèce animale sont hybridées avec des chromosomes d'une seconde espèce animale. On obtient ainsi un spectre de bandes pouvant être comparé avec le spectre produit par un chromosome normal ou caryotype.

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