Crosslinked compositions with improved mechanical performance

Details Crosslinked compositions with improved mechanical performance Crosslinked compositions with improved mechanical performance

B - Operations, Transporting

01

J

B01J 13/00 (2006.01) A61L 27/52 (2006.01) A61L 29/00 (2006.01) A61L 31/00 (2006.01)

Patent

CA 2148336

This invention provides a method of controllably altering the water content of a hydrogel comprising treatment of said hydrogel with a liquid dehydrating composition. There is further provided a method of controllably altering the water content of a hydrogel-containing medical device. The medical devices of the present invention comprise a hydrogel having a controlled (or selected) water level ex vivo lower than the thermodynamic equilibrium water level when in vivo. These medical devices comprise a hydrogel contacted with a liquid dehydrating agent, wherein said medical device has a lower water level ex vivo than the thermodynamic equilibrium water level when the medical device is in vivo. In another aspect of the present invention is provided a method of medical treatment with a medical device which comprises inserting into the body a hydrogel-containing medical device which has been treated with an agent which boosts mechanical performance of the medical device by displacing water from the hydrogel.

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