C - Chemistry – Metallurgy – 08 – F
Patent
C - Chemistry, Metallurgy
08
F
402/225
C08F 220/56 (2006.01) C07K 17/08 (2006.01) C12N 11/08 (2006.01) G01N 33/545 (2006.01)
Patent
CA 1290890
ABSTRACT OF THE DISCLOSURE A water-insoluble, crosslinked polyacrylamide copolymer comprising crosslinked polyacrylamide copolymer chains of recurring monomeric structural units comprising residues of acrylamide, bisacrylamide or analogs thereof, and N,N'-bisacrylylcystamine or analogs thereof. The crosslinked copolymer can be formed into discrete particles characterized by having crosslinking disulfide groups on their external surface which can be reduced to provide exposed chemically active sulfhydryl groups. The activated polyacrylamide particles can be reacted with suitable haptens and other biologically active substances to provide insolubilized forms thereof. MS-1478
548121
Miles Inc.
Osler Hoskin & Harcourt Llp
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