Cryogenic refrigeration system for lyophilization

F - Mech Eng,Light,Heat,Weapons – 26 – B

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F26B 5/06 (2006.01)

Patent

CA 2662505

The cryogenic refrigeration system (2) includes a cryogenic heat exchanger system (105) adapted for vaporizing a liquid cryogen and using the gaseous cryogen to cool heat transfer fluid and a heat transfer cooling circuit (102) that cools the lyophilization chamber (110) as well as the condenser (115). The disclosed heat transfer cooling circuit (102) includes a primary recirculation loop (104) adapted for cooling the lyophilization chamber (110) with the heat transfer fluid, a secondary recirculation loop (106) adapted for cooling a condenser (115) with the heat transfer fluid, and one or more valves (70, 80) operatively coupling the cryogenic heat exchanger system (105), the primary recirculation loop (104), and the secondary recirculation loop (106).

L'invention concerne un système de réfrigération cryogénique pour la lyophilisation. Le système de réfrigération cryogénique selon l'invention comprend un système d'échange thermique cryogénique qui vaporise un liquide cryogène et utilise le gaz cryogène obtenu pour refroidir un fluide de transfert de chaleur, ainsi qu'un circuit de refroidissement par transfert de chaleur qui refroidit la chambre de lyophilisation ainsi que le condenseur. Le circuit de refroidissement par transfert de chaleur selon l'invention comprend une boucle de recirculation primaire servant à refroidir la chambre de lyophilisation à l'aide du fluide de transfert de chaleur, une boucle de recirculation secondaire servant à refroidir un condenseur à l'aide du fluide de transfert de chaleur, ainsi qu'une ou plusieurs vannes qui couplent fonctionnellement le système d'échange thermique cryogénique, la boucle de recirculation primaire et la boucle de recirculation secondaire.

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