Crystal, amorphous form and salt of methyl...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/84 (2006.01)

Patent

CA 2678477

Disclosed is a crystal, an amorphous form, a salt or a hydrate of the salt of methyl N-[3-(6,7-dimethoxy-2- methylaminoquinazolin-4-yl)phenyl]terephthalamic acid, which has a PDE4-inhibiting activity and therefore is useful for the treatment of an allergic disease such as atopic dermatitis.

La présente invention concerne un cristal, une forme amorphe, un sel ou un hydrate de sel de l'acide téréphtalique de méthyle N-[3-(6,7-diméthoxy-2- méthylaminoquinazoline-4-yl)phényle] qui possède une activité inhibant le PDE4 et qui, en conséquence, se révèle très utile lors du traitement de maladies allergiques telle la dermatite atopique.

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