Crystal form of phenylamino pyrimidine derivatives

Details Crystal form of phenylamino pyrimidine derivatives Crystal form of phenylamino pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/506 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2716413

The present invention relates to a particular form of the (3,5-bis trifluoromethyl)-N-[4- methyl-3-(4-pyridin-3yl- pyrimidin-2ylamino)-phenyl]-benzamide (formula I), processes for the preparation thereof, pharmaceutical compositions containing this crystal form, and their use as anti tumor agent in humans. The compound of formula I, also known as AN-019, is: Formula 1 (I)

La présente invention concerne une forme particulière de (3,5-bis trifluorométhyl)-N-[4- méthyl-3-(4-pyridin-3yl-pyrirnidin-2ylamino)-phényl]-benzamide (formule I), ses procédés de préparation, des compositions pharmaceutiques contenant cette forme cristalline et leur utilisation comme agent tumoral chez l'homme. Le composé de la formule (I) est également connu sous le nom de AN- 019.

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