Crystal forms of...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 19/167 (2006.01) A01N 43/04 (2006.01) A61K 31/7076 (2006.01) A61K 49/00 (2006.01)

Patent

CA 2716501

The present invention provides novel crystalline polymorphic forms of 2- cyclohexylmethylidenehydrazino adenosine, also known as binodenoson, methods of making the same, and methods for the manufacture of a pharmaceutical composition by employing such crystal forms, in particular, for the use of binodenoson in a subject, in need thereof, as a pharmacological stress agent to produce coronary vasodilation.

Cette invention concerne de nouvelles formes polymorphes cristallisées de 2-cyclohexylméthylidènehydrazino adénosine (également connu sous le nom de binodénoson), leurs procédés de fabrication, et des procédés de fabrication dune composition pharmaceutique en utilisant ces formes cristallisées, notamment pour lutilisation du binodénoson chez un sujet comme agent pharmacologique antistress en vue de produire une vasodilatation des coronaires.

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