Crystal forms of...

Details Crystal forms of... Crystal forms of...

C - Chemistry, Metallurgy

07

D

C07D 213/74 (2006.01) A61K 31/496 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2425540

The invention relates to crystal forms A and B of 1-[6-chloro-5- (trifluoromethyl)-2-pyridinyl]piperazine.hydrochloride (Org 12962), to methods for the preparation of those crystal forms and to pharmaceutical compositions comprising crystal form B useful in the treatment of depression, anxiety, obesity, or urinary incontinence.

La présente invention concerne des formes cristallines A et B d'hydrochlorure de 1-[6-chloro-5-(trifluorométhyl)-2-pyridinyl]pipérazine (Org 12962), des procédés de préparation de ces formes cristallines, ainsi que des compositions pharmaceutiques comprenant la forme cristalline B, qui sont utilisées dans le traitement de la dépression, de l'angoisse, de l'obésité ou de l'incontinence urinaire.

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