Crystal growth method and solid-state component and...

C - Chemistry – Metallurgy – 30 – B

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C30B 29/58 (2006.01) C07K 1/24 (2006.01) C30B 7/00 (2006.01) C30B 30/02 (2006.01)

Patent

CA 2259030

A method for accelerating the crystallization of biopolymers such as a protein. A crystalline silicon element (70) controlled in the valence electrons in such a way that the concentration of holes or electrons present on the surface can be controlled in accordance with the conditions of a buffer solution (72) containing a biopolymer such as a protein is brought into contact with the solution (72) to thereby crystallize the biopolymer on the surface of the element (70); a plurality of grooves or hollows different in size are formed on the element (70) and the valence electrons are controlled in such a way that the crystallization of the biopolymer in the grooves or hollows can be conducted more rapidly than in the outside of them; and the crystals of the biopolymer grow in the grooves or hollows in contact with the solution (72).

L'invention concerne un procédé permettant d'accélérer la cristallisation de biopolymères tels que des protéines. Un élément de silicium cristallin (70), dont les électrons de valence sont commandés de façon que la concentration de cavités ou d'électrons présents à la surface puisse être réglée en fonction des états de la solution tampon (72) contenant un biopolymère tel qu'une protéine, est mis en contact avec la solution (72), ce qui permet de faire cristalliser le biopolymère à la surface de l'élément (70). Une pluralité de rainures ou de cavités de tailles différentes sont formées sur l'élément (70), et les électrons de valence sont commandés de façon que la cristallisation du biopolymère dans les rainures ou les cavités puisse se faire plus rapidement qu'à l'extérieur desdites rainures ou cavités. Les cristaux du biopolymère croissent dans les rainures ou les cavités en contact avec la solution (72).

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