Crystal modification c of 8-cyano-1-cyclopropyl-7-(1s,...

Details Crystal modification c of 8-cyano-1-cyclopropyl-7-(1s,... Crystal modification c of 8-cyano-1-cyclopropyl-7-(1s,...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4709 (2006.01) A61P 31/04 (2006.01) C07D 209/00 (2006.01) C07D 221/00 (2006.01)

Patent

CA 2362801

The invention relates to a defined crystal modification of 8-cyano-1- cyclopropyl -7- (1S,6S-2,8- diazabicyclo [4.3.0] nonan -8-yl)-6- fluoro -1,4- dihydro -4-oxo -3-quinoline carboxylic acid of f ormula (I), to methods for producing the same and to the use thereof in pharmaceutical formulations. Said crystal modification can be distinguished from other crystal modifications of 8-cyano-1- cyclopropyl -7-(1S,6S-2,8- diazabicyclo [4.3.0] nonan -8-yl) -6- fluoro -1,4- dihydro -4-oxo -3-quinoline carboxylic acid of formula (I) by its characteristic X-ray powder diffractogram and its differential thermodiagram.

L'invention concerne une modification cristalline définie de l'acide 8-cyano -1- cyclopropyl -7- (1S, 6S-2,8- diazabicyclo [4.3.0] nonan -8-yl) -6-fluoro -1,4- dihydro -4-oxo -3-quinoléine -carboxylique de formule (I), des procédés de production de ce composé, ainsi que l'utilisation de ce dernier dans des préparations pharmaceutiques. Cette modification cristalline se distingue des autres modifications cristalline de l'acide 8-cyano-1- cyclopropyl -7-(1S, 6S-2,8- diazabicyclo [4.3.0] nonan -8-yl) -6-fluoro -1,4- dihydro -4-oxo -3-quinoléine -carboxylique de formule (I), par son diffractogramme de rayons X sur poudre, caractéristique, et par son diagramme thermique différentiel.

Affiliated with

Also associated with

Rating

Crystal modification c of 8-cyano-1-cyclopropyl-7-(1s,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Crystal modification c of 8-cyano-1-cyclopropyl-7-(1s,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystal modification c of 8-cyano-1-cyclopropyl-7-(1s,... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1811363