Crystal modification of a n-phenyl-2-pyrimidineamine...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2622808

The invention relates to a new crystalline form of the methanesulfonic acid addition salt of 4-(4--methylpiperazin-l-ylmethyl)-N-[4-methyl-3-(4-pyridin-3--yl) pyrimidin-2-ylamino)phenyl]-benzamide of formula I, which may be used for example for tumour therapy.

La présente invention concerne une nouvelle forme cristalline du sel obtenu par l'addition d'acide méthanesulfonique au 4-(4-méthylpipérazin-l-ylméthyl)-N-¬4-méthyl-3-(4-pyridin-3-yl) pyrimidin-2-ylamino)phényl|-benzamide, représentée par la formule I, laquelle nouvelle forme peut notamment être utilisée dans le traitement de tumeurs.

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