Crystal of benzimidazole compound

Details Crystal of benzimidazole compound Crystal of benzimidazole compound

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/4439 (2006.01)

Patent

CA 2671369

Provided is a crystal of (R)-2-[[[3-methyl-4-(2,2,2- trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole showing an X-ray powder diffraction pattern having characteristic peaks at interplanar spacings (d) of 10.06~0.2, 8.70~0.2, 6.57~0.2, 5.59~0.2 and 4.00~0.2 Angstroms. The present invention provides a stable antiulcer drug superior in the absorbability.

L'invention porte sur un cristal de (R)-2-[[[3-méthyl-4-(2,2,2-trifluoroéthoxy)-2-pyridinyl]méthyl]sulfinyle]-1H-benzimidazole présentant un diagramme de diffraction des rayons X sur poudre ayant des pics caractéristiques à des distances réticulaires (d) de 10,06 ± 0,2, 8,70 ± 0,2, 6,57 ± 0,2, 5,59 ± 0,2 et 4,00 ± 0,2 Angströms. La présente invention porte également sur un médicament antiulcéreux stable et supérieur en ce qui concerne la capacité d'absorption.

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