Crystal of sm3 antibody (fragment) and recognizing epitope,...

Details Crystal of sm3 antibody (fragment) and recognizing epitope,... Crystal of sm3 antibody (fragment) and recognizing epitope,...

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) G01N 33/68 (2006.01) G06F 17/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2300370

A process for preparing a crystal using cadmium. Structure factors or structural coordinates obtained from the crystal of SM3 antibody bound to an epitope can be used to design mimics of the antibody or epitope. Such mimics can be used in the diagnosis or therapy of cancer.

L'invention concerne un procédé de préparation d'un cristal comprenant l'utilisation de cadmium. Des facteurs de structure ou des coordonnées structurelles obtenues à partir du cristal de l'anticorps SM3 lié à un épitope peuvent être utilisés pour construire des analogues de cet anticorps ou de cet épitope. De tels analogues peuvent être utilisés dans le diagnostic ou le traitement du cancer.

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