Crystal structure of a complex of integron integrase from...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/00 (2006.01) C07K 14/28 (2006.01) C12Q 1/02 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/483 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2558125

The present invention relates to the enzyme Integron integrase, and more particularly to the crystal structure of a complex of integron integrase from Vibrio cholerae (VchIntIA) bound to a recombination substrate (VCRbs). The invention further relates to this crystalline structure and its use in the field of DNA recombination and in the design and production of antibiotics and gene manufacture tools.

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