Crystal structure of human soluble adenylate cyclase

C - Chemistry – Metallurgy – 12 – N

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C12N 9/88 (2006.01) G01N 33/00 (2006.01)

Patent

CA 2615753

The invention provides the crystal structure of the solAC catalytic domain. The structure is set out in Tables 1 to 5. The structure may be used in to model the interaction of ligands such as pharmaceutical compounds with this protein, and to determine the structure of related adenylate cyclase molecules.

L'invention concerne la structure cristalline du domaine catalytique solAC. Ladite structure est présentée dans les tables 1 à 5. Elle peut servir à modéliser l'interaction de ligands tels que des composés pharmaceutiques avec cette protéine, et à déterminer la structure de molécules d'adénylate cyclase connexes.

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