Crystaline clindamycin free base

Details Crystaline clindamycin free base Crystaline clindamycin free base

C - Chemistry, Metallurgy

07

H

C07H 15/00 (2006.01) C07H 13/10 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2458644

The antibiotic drug clindamycin is provided as a crystalline free base. Three polymorphic/pseudopolymorphic forms of crystalline clindamycin free base are disclosed. Also provided are pharmaceutical compositions comprising crystalline clindamycin free base. Processes for preparing crystalline clindamycin free base and compositions thereof are also provided along with methods for treating medical conditions with the pharmaceutical compositions.

L'invention concerne le médicament antibiotique clindamycine sous forme de base libre cristalline. Elle concerne aussi trois formes polymorphiques/pseudopolymorphiques de la clindamycine cristalline sous forme de base libre. Elle concerne encore des compositions pharmaceutiques contenant de la clindamycine cristalline sous forme de base libre. Elle concerne enfin des procédés de préparation de la clindamycine cristalline sous forme de base libre, des compositions de ce composé, ainsi que des méthodes de traitement destinées à traiter des troubles médicaux au moyen des compositions pharmaceutiques.

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