Crystalline...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/327 (2006.01) C07D 207/337 (2006.01) C07D 207/34 (2006.01)

Patent

CA 2470114

Novel crystalline forms of atorvastatin calcium designated Fa and Je which are prepared by crystallization from non-aqueous, non-polar solvents at a temperature above 90~C. The crystalline forms are useful as agents for treating hyperlipidemia and hypercholesterolemia.

L'invention porte sur de nouvelles formes cristallines du calcium de l'atorvastatine appelées Fa et Je qui sont préparées par cristallisation à partir de solvants non aqueux, non polaires à une température supérieure à 90 ·C. Les formes cristallines sont utiles comme agents de traitement de l'hyperlipidémie et de l'hypercholestérolémie.

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