C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/4035 (2006.01) A61K 31/444 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2393720
The present invention relates to crystalline 2,5-dione-3-(1-methyl-1H-indol-3- yl)- 4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1H-indol-3-yl]-1H-pyrrole mono- hydrochloride salt, a pharmaceutical formulation containing said salt and to methods for treating cancer and for inhibiting tumor growth using said salt.
La présente invention concerne un sel cristallin de monochlorhydrate de 2,5-dione-3-(1-méthyl-1H-indol-3-yl)-4-¬1-(pyridin-2-ylméthyl)pipéridin-4-yl|-1H-indol-3-yl|-1 H-pyrrole, une formulation pharmaceutique renfermant ledit sel, ainsi que des méthodes pour le traitement du cancer et pour l'inhibition de la croissance des tumeurs à l'aide du sel en question.
Bush Julie Kay
Faul Margaret Mary
Reutzel-Edens Susan Marie
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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