Crystalline 6-n-pyridylmethylaminoindolocarbazole compounds

C - Chemistry – Metallurgy – 07 – H

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C07H 19/23 (2006.01) A61K 31/7056 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2533375

Crystalline 6-N-pyridylmethylamino-12,13-dihydro-2,10 -dihydroxy-12-.beta.-D- glucopyranosyl-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-diones in the form of the free bases as represented by the general formula (I), pharmaceutically acceptable salts of the same, or solvates thereof: (I) wherein R is unsubstituted or hydroxymethylated pyridylmethyl.

La présente invention a trait à des 6-N-pyridylméthylamino-12,13-dihydro-2,10-dihydroxy-12-.beta.-D-glucopyranosyl-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-diones cristallins sous la forme de bases libres tels que représentés par la formule générale (I), dans laquelle R est non substitué ou pyridylméthyle hydroxyméthylé ; leurs sels pharmaceutiquement acceptables, ou leurs solvates.

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