Crystalline alkali metal salts of lansoprazole and their...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01) A61P 31/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2417311

Sodium, magnesium, lithium, potassium, calcium or barium salt of (R)-2-[[[3- methyl-4-(2,2,2-trifluoroethoxy)-2-pyri- dinyl]methyl]sulfinyl]-1H- benzimidazole; and pharmaceutical compositions containing such salts. These novel salts are useful as excellent antiulcer agents.

Cette invention a trait à un sel de sodium, de magnésium, de lithium, de potassium, de calcium ou de baryum de (R)-2-[[[3-méthyl-4-(2, 2, 2-trifluoroéthoxy)-2-pyri-dinyl]méthyl]sulfinyl]-1h-benzimidazole. Elle porte également sur des compositions pharmaceutiques contenant ces sels. Ces derniers se révèlent de remarquables agents anti-ulcéreux.

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