Crystalline and amorphous...

Details Crystalline and amorphous... Crystalline and amorphous...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/495 (2006.01) A61P 13/00 (2006.01) A61P 15/00 (2006.01) A61P 25/06 (2006.01) A61P 25/16 (2006.01) A61P 25/18 (2006.01) A61P 25/20 (2006.01) A61P 25/22 (2006.01) A61P 25/32 (2006.01) A61P 25/34 (2006.01) A61P 25/36 (2006.01)

Patent

CA 2599588

The present invention is directed to crystal and amorphous forms of the 5-HT1A receptor antagonist 4-cyano-N-{(2R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)- piperazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide hydrochloride, as well as compositions thereof and methods of using the same. (I)

La présente invention concerne des formes cristallines et amorphes d'hydrochlorure de 4-cyano-N-{(2R)-2-[4-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-pipérazin-1-yl]-propyl}-N-pyridin-2-yl-benzamide agissant comme antagoniste du récepteur 5-HT1A, ainsi que des compositions correspondantes et leurs méthodes d'utilisation.

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