Crystalline and amorphous forms of efaproxiral sodium

Details Crystalline and amorphous forms of efaproxiral sodium Crystalline and amorphous forms of efaproxiral sodium

A - Human Necessities

61

K

A61K 31/245 (2006.01) A61K 31/195 (2006.01) A61K 31/325 (2006.01) C07C 45/00 (2006.01)

Patent

CA 2563751

There are provided in accordance with the present invention crystalline forms A, B, C, F, G, I, J, P, and Q of efaproxiral sodium. Also provided is the amorphous form of efaproxiral sodium. Also provided are methods of forming the novel polymorphs and the amorphous form of efaproxiral sodium, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.

La présente invention concerne des formes cristallines A, B, C, F, G, I, J, P et Q de sodium éfaproxiral. L'invention concerne également la forme amorphe de sodium éfaproxiral. L'invention concerne en outre des méthodes de formation des nouveaux polymorphes et de la forme amorphe de sodium éfaproxiral, des méthodes thérapeutiques faisant appel à ces derniers ainsi que des formes posologiques pharmaceutiques les contenant.

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