C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 315/06 (2006.01) C07C 315/02 (2006.01) C07C 317/44 (2006.01)
Patent
CA 2416792
The present invention provides an improved process for preparing modafinil, whereby it may be isolated in high purity by a single crystallization. The process produces modafinil free of sulphone products of over-oxidation and other byproducts. The invention further provides new crystalline Forms II-VI of modafinil and processes for preparing them. Each of the new forms is differentiated by a unique powder X-ray diffraction pattern. The invention further provides pharmaceutical compositions containing novel modafinil Forms II-IV and VI.
L'invention concerne un procédé amélioré de préparation de modafinil permettant d'isoler celui-ci en une pureté élevée par une seule cristallisation. Le procédé permet de produire du modafinil exempt de produits de sulfone de sur-oxydation et d'autres sous-produits. L'invention concerne en outre des nouvelles formes cristallines II-VI de modafinil et des procédés de préparation associés. Chaque nouvelle forme est différentiée par un motif unique de diffraction de rayon X sur poudre. L'invention concerne également des compositions pharmaceutiques renfermant des nouvelles formes II-IV et VI de modafinil.
Aronhime Judith
Ceausu Arina
Gershon Neomi
Liberman Anita
Singer Claude
Ridout & Maybee Llp
Teva Pharmaceutical Industries Ltd.
LandOfFree
Crystalline and pure modafinil, and process of preparing the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Crystalline and pure modafinil, and process of preparing the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystalline and pure modafinil, and process of preparing the... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1613489